Fig. 5: Changes in IgG binding following exposure to proteins in carriage. | Nature Communications

Fig. 5: Changes in IgG binding following exposure to proteins in carriage.

From: Genomic and panproteomic analysis of the development of infant immune responses to antigenically-diverse pneumococci

Fig. 5

Violin plots showing the differences in IgG binding to proteins to which individuals were inferred to have been exposed since their birth, relative to those proteins for which there was no evidence of past exposure. Each row of plots corresponds to a different functional type of antigen, classified as described in Fig. 2. Each column of plots corresponds to a different timepoint. Each point corresponds to a measurement of IgG binding to a protein (n = 1773) in an individual (n = 63) at a particular timepoint. The horizontal line within each violin shows the median. The significance of differences between the measurements in each plot was calculated using a Wilcoxon rank sum test. Significant differences are denoted by horizontal bars annotated with the corresponding p values. Source data are provided as a Source Data file.

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