Fig. 2: Overall structure of pendrin.
From: Mechanism of anion exchange and small-molecule inhibition of pendrin
a, b Cryo-EM density map (left) and cartoon representation (right) of the pendrin dimer as viewed from within the plane of the membrane (upper row), or the extracellular side of the membrane (bottom row). The two protomers are colored as cyan and magenta, with lipids in yellow. c. Cartoon representation of a pendrin monomer in two orientations. The transport domain, scaffold domain, and STAS domain are colored violet, cyan, and salmon; respectively. d. Topology of pendrin. Bound Cl- is shown as green spheres.
