Fig. 7: Polygenic risk score association results. | Nature Communications

Fig. 7: Polygenic risk score association results.

From: Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

Fig. 7

Significant associations between thyroid function parameter polygenic scores (PGSs) and diseases in the UKBB. The data points are color-coded by trait (legend) by phenotype groups (x-axis) and -log10(p-value) obtained from two-sided association tests (z-statistics) together with the direction of the effect (y-axis). All results shown passed the Bonferroni significance threshold (p < 0.05/1460).

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