Fig. 8: Thyroid function polygenic risk scores and the risk of thyroid cancer. | Nature Communications

Fig. 8: Thyroid function polygenic risk scores and the risk of thyroid cancer.

From: Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

Fig. 8

Plots of the associations between thyroid parameter polygenic scores TSH (panel a) and FT3 (panel b) and thyroid cancer in deCODE (a; Ncase = 620, Ncontrol = 106,168, b; Ncase = 686, Ncontrol = 119,187). The y-axis shows the probability of thyroid cancer. The x-axis shows the percentage of risk alleles carried out based on a weighted polygenic score. The histogram shows the distribution of the polygenic score in the study sample per trait. Ncase: sample size of cases. Ncontrol: sample size of controls.

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