Fig. 4: Prognostic relevance and summary of molecular classes. | Nature Communications

Fig. 4: Prognostic relevance and summary of molecular classes.

From: A transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker

Fig. 4

Kaplan–Meier curves comparing overall survival (OS) between the two CCA classes for a all the patients employed in the purified cohort; patients with b dCCA; c iCCA; d pCCA only. P values were calculated by log-rank test. e Forest plot displaying anatomical location, stage and molecular subtype as independent prognostic indicators. dCCA, n = 53, iCCA, n = 27, pCCA, n = 84; Stage I + IA/B + II + IIA/B, n = 120, stage IIIA + IIIB + IIIC + IV + IVB, n = 44; C1, n = 58; C2, n = 106. The center of error bars showed observed study effect size. The p values are two-sided and p < 0.05 was considered significant. f Schematic representation of molecular features, prognostic relevance, and potential drug targets in each molecular class. CI confidence interval.

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