Fig. 2: Expression kinetics of VGLL1 in mammalian preimplantation embryos.
From: VGLL1 cooperates with TEAD4 to control human trophectoderm lineage specification
a UMAP visualization showing the different cell types in the human blastocyst at E540. Dots are colored by cell type. Cell types were annotated by cluster-specific gene expression patterns. b Violin plot showing the log-normalized expression of TE genes in different cell types of the human blastocyst at E5. c Left panel: the trajectory of the different cell types in the human blastocyst at E5 reveals two branches: pre-lineage to the TE branch and pre-lineage to the ICM branch. Right panel: colors from dark blue to light blue indicate progression through the pseudotime. d Expression patterns of TE genes along the pseudotime trajectory of cells in the human blastocyst at E5. e UMAP visualization showing the different cell types in the monkey blastocyst at E6-E948. Dots are colored by cell type. Cell types were annotated by cluster-specific gene expression patterns. f Violin plot showing the log-normalized expression of TE genes in different cell types of the monkey blastocyst at E6-E9. g Left panel: the trajectory of the different cell types in the monkey blastocyst (E6-E9) reveals two branches: pre-lineage to the TE branch and pre-lineage to the EPI branch. Right panel: colors from dark blue to light blue indicate progression through the pseudotime. h Expression patterns of TE genes along the pseudotime trajectory of cells in the monkey blastocyst at E6-E9. i UMAP visualization showing the different cell types at the mouse 16-cell stage49. Dots are colored by cell type. Cell types were annotated by cluster-specific gene expression patterns. j Violin plot showing the log-normalized expression of TE genes in different cell types at the mouse 16-cell stage. k Left panel: the trajectory of the different cell types at the mouse 16-cell stage reveals two branches: pre-lineage to the TE branch and pre-lineage to the ICM branch. Right panel: colors from dark blue to light blue indicate progression through the pseudotime. l Expression patterns of TE genes along the pseudotime trajectory of cells at the mouse 16-cell stage.
