Fig. 2: Pre- and post-ZIKV DENV incidence age distributions in Feira de Santana, Salvador and Bahia.
From: Shifting patterns of dengue three years after Zika virus emergence in Brazil
Bars represent age distributions of DENV incidence before (years 2014–2015, hatched) and after (2018–2019, solid) ZIKV. Left and right columns display reported cases and hospitalisations, respectively. From top to bottom: Feira de Santana (A, B), Salvador (C, D) and Bahia (E, F). Insets compare median age of DENV incidence in 2014–15 and 2018–19. Error bars denote the 95% C.I. uncertainty around median estimates and were calculated using a bootstrap procedure (Methods). One-sided permutation tests with \(n=100000\) replicates (Methods) were performed to assess whether the mean age of DENV cases was significantly lower in the post-ZIKV period with respect to the pre-ZIKV period. Making an exception for panel B, incident cases reported in 2018–2019 were significantly younger compared to those reported in 2014-2015, \(p=0\)). In B, the difference in mean ages was negative (−3.02 years) but not statistically significant (\(p=0.136\)). Note that case and hospitalisation data make use of different age groupings.
