Fig. 2: Amino acid sequence and structural characterization of AncEF-1A. | Nature Communications

Fig. 2: Amino acid sequence and structural characterization of AncEF-1A.

From: Evolution of optimal growth temperature in Asgard archaea inferred from the temperature dependence of GDP binding to EF-1A

Fig. 2

a Amino acid sequence alignment of AncEF-1A and its reference ancestral EF-1A proteins that were reconstructed by PAML (PAML-Anc), FastML (FastML-Anc), and IQ-tree (IQ-Anc), respectively. The dots indicate the states that are identical to AncEF-1A. The proposed G-domain, Domain 2, and Domain 3 of the AncEF-1A, and its GDP-binding residues in motif I and motif II are shown. b Distribution of Posterior probabilities for ancestral amino acid states of the AncEF-1A. c A superimposition of the AncEF-1A (green) and its reference ancestral EF-1A proteins (gray). The proposed G-domain, Domain 2, and Domain 3 of the AncEF-1A are shown.

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