Fig. 4: Modeling of the Med25-ACID:DREB2A complex using AF2. | Nature Communications

Fig. 4: Modeling of the Med25-ACID:DREB2A complex using AF2.

From: Molecular switching in transcription through splicing and proline-isomerization regulates stress responses in plants

Fig. 4

A Three structure models of Med25-ACID:DREB2A predicted using AF2 shown with the ABS-RIM induced Med25-ACID CSPs (green). The ABS (red) was predicted to form a single turn helix while the RIM (blue) was predicted to form a 10-residue helix. B Comparison of the packing of Tyr242 and Trp244 in model 1 (left) and 2 (right). C AF2 complex model 2 with the hydrophobic residues shown as spheres and the affinity effect of specific DREB2A variants shown. Source data are provided as a Source Data file.

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