Fig. 3: Moderate spatial modulation of interneuron activity.
From: Subfield-specific interneuron circuits govern the hippocampal response to novelty in male mice
a Calcium activity (peak-normalized) over animal position for PV- and SOM-cells in CA1 (top), CA2/3 (middle) and DG (bottom). Red coloring denotes individual cells with significant spatial tuning. Cells were sorted by their maximum activity along the track. b Fraction of cells with significant spatial tuning (red) and un-tuned cells (gray). c Spatial information (SI) content normalized by the mean activity (left, colored) vs. bootstrap values (right, beige; see Methods) for PV- and SOM-cells in the three hippocampal areas. d Same as in c for spatial coherence (see Methods). e Same as in c, for stability of spatial tuning curves between the first- and second half of each session (see also Supplementary Fig. 5). c–e Wilcoxon signed rank-sum test. Thick lines represent median and interquartile ranges, thin lines in background connect data from individual cells and their respective shuffles. NS not significant; **p < 0.01, ***p < 0.001. All statistical tests are two-sided. For exact p values and statistical comparison of values between IN groups see Supplementary Table 2.
