Fig. 4: Hippocampal area-specific modulation of interneuron activity in the novel context. | Nature Communications

Fig. 4: Hippocampal area-specific modulation of interneuron activity in the novel context.

From: Subfield-specific interneuron circuits govern the hippocampal response to novelty in male mice

Fig. 4

a Mean activity during movement in the familiar (x-axis) and novel (y-axis) context. Dots represent individual cells. b Distribution of mean activity rate during movement in the familiar (left histograms, dark colors) and the novel (right histograms, light colors) environment. c Same as in a (middle) and b (right) for DG SOM-IN axon terminals recorded in the DG molecular layer (ML; see schematic left). d Same as in c, but for DG SOM-IN axon terminal recorded in the DG hilus. b,c,d Wilcoxon signed rank test. Thick lines represent median and interquartile ranges, thin lines in background represent data from individual cells or axons, respectively. NS, not significant; *p < 0.05; ***p < 0.001. All statistical tests are two-sided. For exact p values see Supplementary Table 2.

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