Fig. 3: Post-infusion cytokine level changes in BAL and serum. | Nature Communications

Fig. 3: Post-infusion cytokine level changes in BAL and serum.

From: A phase 1/2 clinical trial of invariant natural killer T cell therapy in moderate-severe acute respiratory distress syndrome

Fig. 3

Cytokine levels measured in EUA patient broken into onset classes (Rapid: onset and durable change within first day post-infusion; Secondary: onset and peak response within first week of infusion; Delayed: onset and peak following first week of infusion) in (A) BAL versus (B) sera at pre- and post-infusion timepoints indicated. For sera, the pre-infusion serum sample was taken on day of infusion with agenT-797 (ID0 Pre). Cytokines were measured by Luminex using a custom multiplex assay (ThermoFisher). Bar colors: Pre-infusion (red); Day post infusion (orange); Day 6 post-infusion (blue): Day 12 post-infusion (purple). Only pre- and a single post-infusion point (ID + 6) were available for sera. Measurements in triplicate, bar represents mean with SD.

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