Fig. 4: A2-APM therapy reduces glioma growth and prolongs survival. | Nature Communications

Fig. 4: A2-APM therapy reduces glioma growth and prolongs survival.

From: Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy

Fig. 4

a Schematic of the treatment regimen. b-c Representative MR images and quantified signal intensity of GL261 tumor-bearing mice treated with saline, free aPD-L1, free PTX, A2-AM, A2-PM, APM, and A2-APM. The yellow dashed lines indicate the tumor area. d Survival curves for the treated and control GL261 tumor mice. e Survival curves for the treated and control G422 tumor mice. n = 5. Statistical significance was calculated by log-rank test. Source data are provided as a Source Data file.

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