Fig. 2: Completion of total syntheses of TTX and 9-epiTTX. | Nature Communications

Fig. 2: Completion of total syntheses of TTX and 9-epiTTX.

From: Total syntheses of Tetrodotoxin and 9-epiTetrodotoxin

Fig. 2

The oxygen atoms are numbered and highlighted in red when they are constructed, and the nitrogen atoms are highlighted in blue; carbon atoms numbered 4, 5, 8a, 9, and 10 are indicated in pink. EDCI·HCl 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride, DMAP 4-dimethylaminopyridine, Tol toluene, NMO N-methylmorpholine N-oxide, NMM N-methylmorpholine, 2,2DMP 2,2-dimethoxypropane, NHPI N-Hydroxyphthalimide, DEAD diethyl azodicarboxylate, CSA camphorsulfonic acid, DCM dichloromethane, PPTS pyridinium p-toluenesulfonate, TFA trifluoroacetic acid.

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