Fig. 4: Crystal structure of SmB/B’58-72 bound to HLA-DR15.
From: Smith-specific regulatory T cells halt the progression of lupus nephritis
a TCR top view of the DR15 bound SmB/B’58-72 with 2 Fo-Fc electron density map, contoured at 1σ. b The peptide is bound in an extended conformation across the DR15 peptide binding groove (side view) with P2-Val, P3-Leu, P5-Arg, and P8-Gln accessible to TCR.
