Fig. 5: Exploration of the ansa chains.
From: Carbene organic catalytic planar enantioselective macrolactonization
a The reactions were conducted with 1 (0.05 mmol, 1.0 equiv.), NHC G (5.2 mg, 20 mol%), DQ (30.6 mg, 150 mol%), HBD-3 (5.2 mg, 15 mol%), and DABCO (1.12 mg, 20 mol%) in toluene/n-heptane (11:9 v/v, 1 mM) under N2 atmosphere at 100 °C for 12 h; Isolated yields.
