Fig. 1: The tissue-specific changes of miRNA transcriptomes during worm ageing.
From: Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans
a A depiction of the tissue-specific analysis of miRNA transcriptomes during worm ageing. Created with BioRender.com. b The volcano plots showing the differentially expressed miRNAs in indicated ageing tissues. MiRNAs with a P value smaller than 0.05 were considered significantly changed by ageing. Two-sided t-test without adjustments for multiple comparisons. c, d Principal component analysis (c) and hierarchical clustering (d) of the miRNAomic datasets of indicated tissues from the worms at day 1 (D1) or day 8 (D8) of adulthood. Neu neuron, Int intestine, BWM body wall muscle, Hyp hypodermis, Coel coelomocyte.
