Fig. 1: Age curves of standardized and zero-centered mean values of GM and WM features per hemisphere.
From: Brain asymmetries from mid- to late life and hemispheric brain age
A cubic smooth function (s) with k = 4 knots was applied to plot the relationship between age and brain features correcting for sex and scanner site (F): \(\hat{age}=s(F)+sex+site\) using restricted maximum likelihood (REML). The grey shaded area indicates the 95% CI. All age-relationships were significant (padj < 3.4 × 10−64). Sample sizes for diffusion metrics: NdMRI = 39, 637, sample size for T1 metrics: \({N}_{{T}_{1}}=48,040\). Source data are provided in Source Data file 1.
