Fig. 2: T1-weighted and dMRI features linear asymmetry-age-associations.
From: Brain asymmetries from mid- to late life and hemispheric brain age
The plot presents the standardized (sex- and site-corrected) regression slopes versus Bonferroni-adjusted -log10 p-values. Modelling was done using Eq. (2): \(\hat{age}={\beta }_{0}+{\beta }_{1}\times F+{\beta }_{2}\times Sex+{\beta }_{3}\times Site\), where F is the respective brain feature. Labelling was done separately for T1-weighted and dMRI indicating the 10 most significantly associated features (five for β > 0 and five for β < 0). ILF inferior longitudinal fasciculus, Cereb.Peduncle Cerebral peduncle, Rostro-mid. thickness Rostro-middle thickness, SLFT Superior longitudinal fasciculus (temporal part), Fornix-Str.Term. Fornix-stria terminalis tract, Caud. ant. cingulate Caudal anterior cingulate. Sample sizes for diffusion metrics: NdMRI = 39,637, sample size for T1 metrics: \({N}_{{T}_{1}}=48,040\). Source data are provided in Source Data file 2.
