Fig. 5: CD103-expressing T cells are proficient producers of pro-inflammatory cytokines. | Nature Communications

Fig. 5: CD103-expressing T cells are proficient producers of pro-inflammatory cytokines.

From: Etrolizumab-s fails to control E-Cadherin-dependent co-stimulation of highly activated cytotoxic T cells

Fig. 5

Representative and quantitative flow cytometry of IFNγ and TNFα expression (A) and quantitative flow cytometry of IL17A as well as IL17A and IFNγ co-expression (B) by stimulated and TGFβ1-treated CD103+/− peripheral blood CD4+ T cells. n = 7–9 patients with Crohn’s disease (CD) or non-IBD controls (CON) as indicated. Significant outliers were detected by 1% ROUT test and removed from analysis. Two-way ANOVAs with Sidak’s multiple comparisons test were performed. Data are displayed as box-whisker plots from minimum to maximum. The center line indicates the median with box limits defining the quartiles. Source data are provided as a Source Data file.

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