Table 1 Characteristics of CLL patients with IGLV3-21R110 mutation
Patient | Sex | Age range | Treatment | del17q | CDR3 (aa) | IGHV | IGHD | IGHJ | IGHV status |
|---|---|---|---|---|---|---|---|---|---|
CLL001 | m | n/a | no | no | CALDRDGMDVW | IGHV3-69-1 | IGHD3-22 | IGHJ6 | M |
CLL010 | m | n/a | no | no | CAVDRNGMDVW | IGHV3-21 | IGHD5-18 | IGHJ6 | M |
CLL054 | m | n/a | yes | no | CARDTHDTNGYPRWYYGLDVW | IGHV3-11 | IGHD3-22 | IGHJ6 | M |
CLL062 | m | n/a | yes | no | CANGGGDGEYDYW | IGHV4-39 | IGHD3-10 | IGHJ4 | M |
CLL162 | m | 50–60 | no | no | CARGVPRPHW | IGHV3-48 | IGHD1-14 | IGHJ4 | M |
CLL306 | m | 60–70 | no | no | CARDLYYYDSSGYYSGFFDYW | IGHV1-46 | IGHD3-22 | IGHJ4 | UM |
CLL350 | f | 70–80 | yes | no | CARDVVDYVWGSYLRAFDIW | IGHV1-69 | IGHD3-16 | IGHJ3 | UM |
CLL362 | f | 60–70 | yes | no | CARDQVAVAGCFDYW | IGHV4-61 | IGHD6-19 | IGHJ4 | M |
CLL374 | m | 60–70 | yes | no | CARDFVEPGYW | IGHV3-48 | IGHD6-13 | IGHJ5 | M |
CLL381 | f | 60–70 | yes | no | CARGAGAGDYW | IGHV3-48 | IGHD6-13 | IGHJ4 | M |
CLL385 | m | 50–60 | yes | no | CARDVGGDNSGAFDIW | IGHV2-26 | IGHD2-21 | IGHJ3 | UM |
CLL401 | m | 70–80 | yes | no | CARDQNTMDVW | IGHV3-21 | IGHJ6 | UM | |
CLL424 | f | 50–60 | yes | no | CARPCYDDNSDAFDIW | IGHV3-7 | IGHD3-22 | IGHJ3 | UM |
CLL425 | f | 50–60 | yes | no | CARVENDGGYCSGGSCYPIW | IGHV3-48 | IGHD2-15 | IGHJ4 | M |
CLL435 | m | 60–70 | no | no | CARDPGVVAATDSAIW | IGHV3-48 | IGHD2-15 | IGHJ4 | M |
CLL438 | m | 80–90 | yes | no | CARDQNAMDVW | IGHV3-21 | IGHJ6 | M | |
CLL442 | f | 70–80 | yes | no | CVKGGPGDGGNPFDPW | IGHV4-34 | IGHD4-23 | IGHJ5 | UM |
