Fig. 6: Network and pathway analyses of genes contributing significantly to ApoB.
From: A method to estimate the contribution of rare coding variants to complex trait heritability
a Gene-disease heatmap, created with DisGeNET, for the genes contributing significantly to the RV heritability of ApoB. The intensity of colour is proportional to the strength of evidence for gene-disease-association, with darker colour representing a greater level of evidence. b Network cluster representing biological mechanisms influenced by genes contributing significantly to ApoB heritability estimates. The nodes represent gene-sets, the edges represent known interaction between biological pathways. Node size reflects the number of genes in the gene-set. More intense colour indicates higher enrichment value.
