Fig. 4: Absolute risk of multi-drug resistance over 20 years.
From: Assessing emergence risk of double-resistant and triple-resistant genotypes of Plasmodium falciparum
Each boxplot (N = 100 simulations) shows the sum of AUCs across all five maximally-resistant genotypes (Table 1). Boxplot whiskers are 1.5 times the IQR. AUC comparisons between MFT and 5-year cycling and AUC comparisons between MFT and adaptive cycling are assessed with a Mann-Whitney test, and p-value markers (testing whether MFT has lower AUC) are placed next to each boxplot with p < 0.05 (*) or p < 10−4 (**). In the upper-right panel, the red p-value marker indicates that MFT (median AUC = 0.23 risk days) has higher AUC than the adaptive cycling strategy (median AUC = 0.10 risk days) with p = 0.037.
