Table 1 List of five maximally-resistant genotypes tracked in this analysis

From: Assessing emergence risk of double-resistant and triple-resistant genotypes of Plasmodium falciparum

Name

Genotype

Treatment Failure

DHA-PPQ, AQ triple-resistant

580Y, 76T, 86Y, Y184, PPQ-resistance present in pfcrt

58.5% for DHA-PPQ 26.5% for ASAQ 9.2% to 20.5% for AL

DHA-PPQ, LUM triple-resistant

580Y, K76, N86, 184F, PPQ-resistance present in pfcrt

58.5% for DHA-PPQ 5.2% for ASAQ 27.7% to 43.0% for AL

DHA-PPQ double-resistant

580Y, PPQ-resistance present in pfcrt

58.5% for DHA-PPQ

ASAQ double-resistant

580Y, 76T, 86Y, Y184

26.5% for ASAQ

AL double-resistant

580Y, K76, N86, 184F

27.7% to 43.0% for AL

  1. For all five genotypes, pfmdr1 copy number can be single or multiple.