Table 1 List of five maximally-resistant genotypes tracked in this analysis
From: Assessing emergence risk of double-resistant and triple-resistant genotypes of Plasmodium falciparum
Name | Genotype | Treatment Failure |
---|---|---|
DHA-PPQ, AQ triple-resistant | 580Y, 76T, 86Y, Y184, PPQ-resistance present in pfcrt | 58.5% for DHA-PPQ 26.5% for ASAQ 9.2% to 20.5% for AL |
DHA-PPQ, LUM triple-resistant | 580Y, K76, N86, 184F, PPQ-resistance present in pfcrt | 58.5% for DHA-PPQ 5.2% for ASAQ 27.7% to 43.0% for AL |
DHA-PPQ double-resistant | 580Y, PPQ-resistance present in pfcrt | 58.5% for DHA-PPQ |
ASAQ double-resistant | 580Y, 76T, 86Y, Y184 | 26.5% for ASAQ |
AL double-resistant | 580Y, K76, N86, 184F | 27.7% to 43.0% for AL |