Fig. 6: Abolishing potential degradations of MSA improved 3-HP production.
From: Increased CO2 fixation enables high carbon-yield production of 3-hydroxypropionic acid in yeast
a Candidate enzymes that could potentially degrade 3-HP. b Deletion of UGA1 combined with overexpression of the MCR-C domain using CCW12 promoter could improve the 3-HP production to 11.25 g/L. Abbreviations were defined in Supplementary Data 5 and 6. The defined minimal medium with 0.15 g CaCO3 for each flask was used for the 3-HP production. All data were presented as mean ± SD of biological triplicates. Significant comparisons of two groups were indicated in the graphs statistical analysis performed using a two-tailed unpaired Student’s t-test (*p < 0.05, **p < 0.01, ***p < 0.001). Source data are provided as a Source Data file.
