Fig. 2: Major structural features and nucleotide pair-wise comparisons of group 2 capsules in Escherichia coli ST131.

Nucleotide comparisons between the sub-clade C2 strain JJ1886, clade C outgroup genome CD306, and clade C2 strain O25:H4, highlighting differences between the K14, K5 and an unprecedented capsular region. The capsule loci in strain O25b:H4 is present in the GB-WLS.C2 draft genomes. Blue shading indicates nucleotide identity between sequences according to BLASTn (95 to 100%). Key genomic regions are indicated: IS: red (185 bp fragment from IS110 family), conserved capsular regions I and III: pink, differing capsular regions (region II): orange and yellow, other CDSs: black. Image created using Easyfig34.