Fig. 7: Mechanistic investigations. | Nature Communications

Fig. 7: Mechanistic investigations.

From: Nickel-catalyzed electrophiles-controlled enantioselective reductive arylative cyclization and enantiospecific reductive alkylative cyclization of 1,6-enynes

Fig. 7

a Reductive cyclization of 1,7-enynes. b Reductive cyclization of alkenyl iodides. c Crossover experiment. d Stoichiometric experiment with aryl-Ni(II) complexes. e Quench of alkenylnickel intermediates. f Radical trapping experiment. TEMPO tetramethylpiperidine oxide. g Stoichiometric experiment with Ni(0). h Ring opening reaction. i Ring, closing reaction.

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