Fig. 5: The treatment of implant infection with PH-CpBT in vivo. | Nature Communications

Fig. 5: The treatment of implant infection with PH-CpBT in vivo.

From: Ultrasound-activated piezo-hot carriers trigger tandem catalysis coordinating cuproptosis-like bacterial death against implant infections

Fig. 5

a Schematic illustration of infected modified PEKK scaffolds and animal experimental treatment in therapeutic. b Photographs of bacterial colonies and turbid liquid. c Quantitative analysis of bacterial turbid liquid by OD 600. A representative image of three biological replicates from each group was shown. d H&E images and e semi-quantification of neutrophil in the infected bone tissues surrounding the implants. The red arrows represented neutrophils, and the green arrows represented lymphocytes. A representative image of three biological replicates from each group was shown. f Giemsa staining images and g semi-quantification of bacteria in the infected bone tissues surrounding the implants. The black arrows represented bacteria. A representative image of three biological replicates from each group was shown. c, e, g n = 3 biologically independent samples; ANOVA followed by Tukey’s multiple comparisons; data were presented as mean values ± SD; error bars = SD. Significant differences between groups were indicated as ****p < 0.0001, ***p < 0.001, **p < 0.01, and *p < 0.05. Source data are provided as a Source Data file.

Back to article page