Fig. 6: The number and speed of new bone growing into the scaffold. | Nature Communications

Fig. 6: The number and speed of new bone growing into the scaffold.

From: Ultrasound-activated piezo-hot carriers trigger tandem catalysis coordinating cuproptosis-like bacterial death against implant infections

Fig. 6

a Mico-CT of femoral condyle, from up to down, reconstruction of the defect and new bone ingrowth in the scaffolds, top view of new bone, side view of new bone. The green and pink cylinder showed the new bone growth for the first four weeks and the next four weeks, respectively. A representative image of four (4 W) and six (8 W) biological replicates from each group was shown. Quantitative statistics of bone regeneration related index in 3D reconstruction by micro-CT including b BV/TV, c BMD, d Tb. N, e Tb. Sp, and f Tb. Th. g Calcitonin (green) and alizarin red (red) marked new bone. A representative image of three biological replicates from each group was shown. h Quantitative statistics of MAR from 4th week to 6th week. b–f n = 4 biologically independent samples (4 W), n = 6 biologically independent samples (8 W); h n = 4 biologically independent samples. b–h ANOVA followed by Tukey’s multiple comparisons; data were presented as mean values ± SD; error bars = SD. Significant differences between groups were indicated as ****p < 0.0001, ***p < 0.001, **p < 0.01, and *p < 0.05. Source data are provided as a Source Data file.

Back to article page