Fig. 7: The microstructure and mechanism of new bone ingrowth. | Nature Communications

Fig. 7: The microstructure and mechanism of new bone ingrowth.

From: Ultrasound-activated piezo-hot carriers trigger tandem catalysis coordinating cuproptosis-like bacterial death against implant infections

Fig. 7

a H&E and Goldner staining of undecalcified tissue around the implant at 4th and 8th weeks post-surgery. A representative image of three biological replicates from each group was shown. b Quantification of H&E in the implants at 8th weeks. c Quantification of Goldner positive area in the implants at 8th weeks. d Immunofluorescence staining of CD31, BMP-2, and RUNX2 surrounding tissues of implants at 8th weeks post-surgery. A representative image of three biological replicates from each group was shown. Quantification of e CD31, f BMP-2, and g RUNX2 immunoreactivity within the implants. b, c, e, f, g n = 3 biologically independent samples; ANOVA followed by Tukey’s multiple comparisons; data were presented as mean values ± SD; error bars = SD. Significant differences between groups were indicated as ****p < 0.0001, ***p < 0.001, **p < 0.01, and *p < 0.05. Source data are provided as a Source Data file.

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