Table 1 Optimization of reaction conditions

From: Accessing ladder-shape azetidine-fused indoline pentacycles through intermolecular regiodivergent aza-Paternò–Büchi reactions

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  1. aReactions were performed with indole 1a (0.2 mmol), imine 2 (0.1 mmol), and photosensitizer in MeCN (2 mL) under irradiation with purple LEDs (λmax = 405 nm, for entries 1–5 and 15) or blue LEDs (λmax = 455 nm, for entries 6-14) at room temperature under nitrogen for 24 h.
  2. bYields are of isolated product 3aa.
  3. cIn dark.
  4. dCatalyst loading was 10 mol%.
  5. TXO thioxanthone, PC photocatalyst, Ts Tosyl, Boc tert-butoxycarbonyl, ND not determined.
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