Fig. 1: Genome characterization of three Stephania species.
From: Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery
A Inferred phylogenetic tree and divergence time estimation of 14 flowering plant species including three Stephania species, namely, Stephania japonica, Stephania yunnanensis, and Stephania cepharantha. B Genome-wide all-against-all Hi-C interaction map of the three Stephania species. C Near telomere-to-telomere assembly of S. japonica. Orange bars indicate centromere locations, the yellow bar indicates a gap in chromosome 9, and violet triangles indicate telomere locations. D Circos plots from the periphery toward the center showing chromosome length (Mb), chromosome number, gene density (red columns), repeat percentage (blue violet lines), and telomere and centromere locations (black and orange columns, respectively). E Synonymous substitutions per synonymous site (KS) distributions of paralogous genes (upper panel) and orthologous genes (lower panel) among the three Stephania genomes, Coptis chinensis, and Vitis vinifera. F Dot plots of orthologs between S. japonica and V. vinifera. Red and purple circles highlight two examples suggesting a 2:3 syntenic proportion resulting from whole genome duplication or triplication. Source data are provided as a Source Data file.
