Table 2 EC50 assay of BIAs and remdesivir against SARS-CoV-2 live virus

From: Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery

Compound

SARS-CoV-2 (Vero E6) EC50 (μM)

Cepharanthine (1)

2.19

Tetrandrine (3)

3.13

Berbamine (10)

19.95

Fangchinoline (19)

5.01

Isotetrandrine (14)

4.47

Cycleanine (15)

8.91

Daurisoline (17)

12.50

Remdesivir (30)

2.19