Fig. 2: Preparation, polydopamine modification, and mechanophysical characterization of porous synthetic polymer microspheres. | Nature Communications

Fig. 2: Preparation, polydopamine modification, and mechanophysical characterization of porous synthetic polymer microspheres.

From: Elastic porous microspheres/extracellular matrix hydrogel injectable composites releasing dual bio-factors enable tissue regeneration

Fig. 2

A SEM images showing the macro-morphology and pore structure of different microspheres. Purple box: central region; red box: marginal region. B Respective statistical results of different microspheres’ diameter. Data are presented as mean ± SD (n = 21 independent microspheres, from three independent batches of samples). C Statistical results of different microspheres’ pore sizes. Data are presented as mean ± SD (n = 34 independent pore sizes, from three independent batches of samples). D, E 2D and 3D images (AFM) showing the surface roughness of porous PLCL microspheres before and after PDA modification, as well as corresponding statistical analysis. Data are presented as mean ± SD (n = 4 independent samples). F XPS analysis of C, O, and N peak changes before and after PDA modification, dotted box: local enlargement of the N 1s peak. G The injectability of different microspheres. I–III: Morphology pattern diagrams of different microspheres after injection with a syringe. Red box: high magnification images; Red arrow: microsphere fragmentation/deformation area. H Recovery rate of different microspheres after compressing once for 30 s or 2 min. Data are presented as mean ± SD (n = 4 independent samples). ****P < 0.0001, ns: no significant difference, one-way ANOVA, multiple comparisons. I, J The morphology of different microspheres after repeated compressions and the corresponding recovery rate statistics.

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