Fig. 3: Identification of differential gene co-expression modules between MPI and the other bat species.

a Network analysis dendrogram showing modules based on the co-expression topological overlap of genes among different bat species and mouse. The color bars below give information on module membership. b The distribution of mean differences of the module eigengene (ME) between MPI and other species across 34 gene co-expression modules. The upregulated module M1 and downregulated module M2 in MPI are highlighted. c The ME value of M1 is significantly larger for MPI than those for other bat species and mouse. The ME value of M2 is significantly less for MPI than those for other bat species and mouse. The Szechwan myotis (Myotis altarium; MAL), the least horseshoe bat (Rhinolophus pusillus; RPU), the greater horseshoe bat (Rhinolophus ferrumequinum; RFE), the Chinese rufous horseshoe bat (Rhinolophus sinicus; RSI), the great leaf-nosed bat (Hipposideros armiger; HAR), and the Leschenault’s Rousette (Rousettus leschenaultii; RLE). The P values are from two-tailed Student’s t tests. ***P < 0.001. Source data are provided as a Source Data file.