Fig. 4: Functionality alterations in the ileal mucosal virome in CD.

The differential virome functions between CD and HC were identified via MaAsLin2 controlling for medications, dietary habit, and geography. Only function modules with BH-FDR q < 0.2 (p < 0.05) were shown. Statistical significance was determined by a two-tailed multivariable association test, and adjusted by the BH-FDR adjustment.