Fig. 2: Characterization of partially methylated domains in the lamprey genome.
From: Extensive DNA methylome rearrangement during early lamprey embryogenesis
A Browser track depicting per CpG mCG levels for PMDs (PMD partially methylated domain, dark blue) on scaffold PIZI01000031v1. All lamprey mCG values in this figure are from merged WGBS replicates. B Cluster heatmap of Spearman correlation of genomic PMD overlap. C Percentage of genome impacted by changes in PMD state in pairwise comparisons of samples (E egg, S sperm, 1 day 1, 2 day 2). D Browser track depicting mCG profiles of reprogrammed PMDs. E Schematic depicting major PMD reprogramming dynamics and the percentage of the genome associated with reprogramming events. UMR - unmethylated region, LMR - lowly methylated region, HyperMR- hypermethylated region. F Proportion of discordant reads (PDR) and mCG levels at reprogrammed PMDs. PDR and mCG levels are calculated from merged WGBS replicates for each tissue.
