Table 3 MRI changes at baseline and one year after injection
Patient # | MRI pre-injection | MRI at one year | Comments |
|---|---|---|---|
Patient 1 | Focal injury to the cervical cord at C3 with diffuse increased T2 signal in the cervical and thoracic cord below this level. | No significant change from the prior examination | N/A |
Patient 2 | Myelomalacia of the thoracic spinal cord at the T11 and T12 levels | No significant change from the prior examination | N/A |
Patient 3 | Focal T2 hyperintensity within the cervical cord at the C6-7 level consistent with posttraumatic myelomalacia. | No significant change from the prior examination | Mildly increased clumping of the cauda equina nerve roots at the L4-L5 level. |
Patient 4 | Central cord signal abnormality that extends from T11 to the conus medullaris at T12-L1. More equivocal central T2 signal abnormality also extends cranially up to T6-T7. | No significant change from the prior examination | Clumping/thickening of the lumbar nerve roots. |
Patient 5 | Cystic myelomalacia in the lower thoracic cord. | No significant change from the prior examination | Clumping of the roots of the cauda equina without evidence of nodular enhancement |
Patient 6 | Cord signal abnormality consistent with myelomalacia that extends from C4-5 to C7, with subtle cord signal abnormality on the Sag IR sequence extending inferiorly to T2. | No significant change from the prior examination | Development of thickening, clumping, and minimal enhancement of the nerve roots of the cauda equina. |
Patient 7 | Mild T2 signal abnormality in the dorsal cord, presumably related to Wallerian degeneration. | No significant change from the prior examination | New nodularity along the cauda equina at L2, L3, and in the cul-de-sac. Evidence of new prominence of the lower nerve roots. |
Patient 8 | There is severe myelomalacia of the cervical spinal cord extending from the C5 through mid-C7. There is an irregular intrathecal enhancement that is involving the spinal cord, most prominently at the C6 level. | No significant change from the prior examination | Interval increase in the segmental enhancement of cauda equina nerve roots as well as leptomeningeal enhancement of the distal cord, extending cephalad to at least approximately mid-thoracic levels. |
Patient 9 | Non-enhancing T2 hyperintense signal change within the spinal cord at the level of the C5-C6 interspace consistent with sequela of prior trauma. | No significant change from the prior examination | New clumping and peripheral displacement of the cauda equina nerve roots with mild enhancement. |
Patient 10 | Marked myelomalacia of the cervical spinal cord extending from the lower body of C4 to the midbody of C7 with marked ventral kinking of the cord at the level of C5. | No significant change from the prior examination | Signal abnormality and clumping along with the cauda equina nerve roots at L3. |
