Fig. 1: The impact of PEG sensitization and anti-PEG antibodies on the efficacy of a PEG hydrogel-based tissue engineering strategy was assessed via implantation of PEG-based MAP hydrogels in a calvarial defect model.
From: Impact of PEG sensitization on the efficacy of PEG hydrogel-mediated tissue engineering
Schematic of A materials and fabrication of PEG microparticles and annealing of MAP hydrogels, and B timeline of the animal study. The calvarial defect model was chosen because it is widely used to evaluate the efficacy of biomaterials and therapeutics for bone regeneration. Tissue samples were collected at 3 and 6 weeks post-implantation. Tissue processing and data analysis were conducted immediately following the end of each time point. Created with BioRender.com.
