Fig. 2: Naked mole-rats exhibit distinct cardiac gene profile expression unrelated to any of the other subterranean genera highlighting genetic adaptations at the mitochondrial level. | Nature Communications

Fig. 2: Naked mole-rats exhibit distinct cardiac gene profile expression unrelated to any of the other subterranean genera highlighting genetic adaptations at the mitochondrial level.

From: Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles

Fig. 2

A Hierarchical clustering of samples by similarity based on the expression level of all genes. B Heatmap with predicted differentially expressed genes encoding transcription factors (TF); X axis represents each comparing sample (relative to the NMR), Y axis represents DEGs. Colouring indicates the log2 transformed fold change (high: red, low: blue). C Normalised comparison of the 30 most expressed genes in NMR hearts and (D) C57/BL6 mouse hearts—expressed as fragments per kilobase of transcript per million mapped reads. Nd2* and Nd4* in (C) are smaller novel transcripts (BGI_novel_G000346 and BGI_novel_G001276 respectively; Supplementary Data 2). Source data are provided as a Source Data file.

Back to article page