Fig. 3: Volcano plot showing differentially expressed genes.

A–H show each respective pairwise comparison between the naked mole-rat (NMR) and the other species in the RNAseq dataset. Y axis shows statistical significance as the −Log10P values while the x axis the Log2 fold change in gene expression (positive values represent overexpression in the NMR). Relevant genes that were identified and discussed in the text are labelled. The default cut-off for log2FC is >|2| and the default cut–off for P value is 10−6, denoted by the dotted lines. Points are coloured as follows: grey (not significant P > 10-6, log2FC < |2|), green (not significant P > 10−6, log2FC > |2|), blue (significant P < 10−6, log2FC < |2|), red (significant P < 10-6, log2FC > |2|). Source data are provided as a Source Data file.