Fig. 5: Recombination rates (krec) and s-values for resistant and compensated strains.
From: Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism
Absolute values of krec (triangles; left y-axis) and s-values (circles; right y-axis). A Compensated mutants of E. coli isolated on 24X MIC tobramycin after 100 generations (red). B Compensated mutants of E. coli isolated on 24X MIC gentamicin after 100 generations (blue). C Compensated mutants of K. pneumoniae isolated on 24X MIC gentamicin after 100 generations (green). D Compensated mutants of S. Typhimurium isolated on 24X MIC tetracycline after 100 generations (pink). The darker shade represents the high copy number parental strains isolated at 24X MIC and the lighter shades represent the three independent lineages from the compensatory evolution experiment. Source data are provided as a Source Data file.
