Fig. 5: Lead SNPs at GWAS and TWAS loci are associated with cardiovascular traits in UK Biobank. | Nature Communications

Fig. 5: Lead SNPs at GWAS and TWAS loci are associated with cardiovascular traits in UK Biobank.

From: Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation

Fig. 5

The nearest gene is indicated on the x-axis; * denotes TWAS loci. The traits are from the following categories: blood lipids (orange), blood pressure (brown), anthropometric traits (gray), cardiovascular diseases (red), diabetes (blue) and others (green). The effect size and statistical significance of the genetic association with the phenotype in UK Biobank are illustrated by the color (Z-score) and the size of the bubble (p-value).

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