Table 1 Demographic characteristics of the participants

From: Development and validation of an interpretable model integrating multimodal information for improving ovarian cancer diagnosis

 

SYSUCC

CQUCC

 

Training

Validation

Internal test dataset

External test dataset

No. of patients

532

63

129

387

Age (y)

  Mean ± SD

48 ± 12

46 ± 13

48 ± 14

43 ± 12

  Range

16–82

16–69

20–79

18–83

Menopausal status

  Premenopausal

291 (54.7)

37 (58.7)

70 (54.3)

272 (70.3)

  Postmenopausal

241 (45.3)

26 (41.3)

59 (45.7)

115 (29.7)

CA125 concentration

  Mean ± SD

1218 ± 3119

919 ± 1923

1274 ± 2902

245 ± 2413

  Range

4–37,827

9–12,684

7–20,308

2–46,090

Lesion diameter (mm)

  Mean ± SD

74.0 ± 36.5

74.8 ± 31.9

72.4 ± 32.9

71.2 ± 35.0

  Range

10–224

30–161

15–164

19–334

Histological type

  Benign (%)

215 (40.4)

27 (42.9)

54 (41.9)

306 (79.1)

  Teratoma

72 (33.5)

12 (44.5)

20 (37.0)

86 (28.1)

  Endometriosis

48 (22.3)

9 (33.3)

17 (31.4)

102 (33.3)

  Cyst

33 (15.3)

2 (7.4)

5 (9.3)

33 (10.8)

  Cystadenoma

19 (8.8)

2 (7.4)

4 (7.3)

50 (16.4)

  Inflammation

17 (8.0)

0 (0.0)

2 (3.7)

1 (0.3)

  Corpus luteum

11 (5.1)

0 (0.0)

1 (1.9)

14 (4.7)

  Thecoma

6 (2.8)

1 (3.7)

1 (1.9)

5 (1.6)

  Fibroma

4 (1.9)

0 (0.0)

1 (1.9)

5 (1.6)

  Hydrosalpinx

2 (0.9)

0 (0.0)

2 (3.7)

5 (1.6)

  Other

3 (1.4)

1 (3.7)

1 (1.9)

5 (1.6)

 Malignant (%)

317 (59.6)

36 (57.1)

75 (58.1)

81 (26.5)

  Serous carcinoma

237 (74.8)

23 (63.9)

60 (80.0)

47 (58.0)

  Borderline tumor

30 (9.5)

6 (16.7)

5 (6.6)

16 (19.7)

  Endometrioid carcinoma

9 (2.8)

1 (2.8)

2 (2.7)

5 (6.2)

  Clear cell

9 (2.8)

3 (8.3)

2 (2.7)

2 (2.5)

  Other

32(10.1)

3 (8.3)

6 (8.0)

11 (13.6)

  1. Data in parentheses are percentages. SD Standard deviation.