Table 3 ROC information for serum or urine biomarker panels

From: NMR and MS reveal characteristic metabolome atlas and optimize esophageal squamous cell carcinoma early detection

Predicted probability panels

AUC (95% CI)

Cut-off

SE

SP

Accuracy

PPV

NPV

Youden

Serum panel (five metabolites)

0.984 (0.968–1.000)

0.502

0.955

0.943

0.948

0.926

0.965

0.897

Urine panel (five metabolites)

0.930 (0.913–0.976)

0.833

0.850

0.949

0.889

0.962

0.804

0.799

  1. AUC areas under the curve, 95% CI 95% CI confidence interval, SE sensitivity, SP specificity, PPV positive predictive value, NPV negative predictive value.
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