Table 1 Univariate Cox proportional hazard analyses on 123 HGSOC patients from Study cohort 1 (Study group 1; Supplementary Table 1)

From: Tertiary lymphoid structures and B cells determine clinically relevant T cell phenotypes in ovarian cancer

Variable

HR (95% CI)

p value

Age

 

1.02 (1.00–1.04)

0.034

Stage

I

  
 

II

0.70 (0.22–2.21)

0.546

 

III

2.27 (1.18–4.35)

0.014

 

IV

1.37 (0.47–3.94)

0.565

Debulking

R0

  
 

R1

1.49 (0.58–3.82)

0.401

 

R2

1.86 (1.17–2.94)

0.008

CA125

 

1.10 (0.97–1.24)

0.114

CD8+ T cells

 

0.85 (0.73–0.99)

0.041

CD20+ B cells

 

0.85 (0.75–0.96)

0.011

DC-LAMP+ DCs

 

0.80 (0.64–1.01)

0.067

NKp46+ NK cells

 

0.92 (0.73–1.15)

0.471

TLS clusters

CL1

  
 

CL2

0.53 (0.32–0.87)

0.012

 

CL3

1.06 (0.57–1.96)

0.851

GZMB+CD8+ T cells

 

0.87 (0.76–0.99)

0.045

PD1+CD8+

 

0.86 (0.69–1.06)

0.172

TCF1+PD1+CD8+

 

0.75 (0.53–1.04)

0.098

TIM3+PD1+CD8+

 

0.86 (0.68–1.07)

0.173

  1. Statistical significance was calculated by Univariate cox proportional hazard analyses. HR and p values are indicated.
  2. TLS tertiary lymphoid structures.
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