Fig. 4: NCS preferring units respond earlier, receive more surround modulation, and may correspond to complex cells or putative inhibitory neurons.
a The response latencies to NCS and LDG stimuli. Points above the dotted line indicate a later response to NCS stimuli relative to LDG stimuli. Each point represents a single unit. b IGR plotted against latency of responses evoked by black rectangles. The gray line represents a least squared fit to the data. The r value and p value (two-sided t-test) for Pearson’s correlation coefficient are shown. c IGR plotted against surround modulation index. Plotting conventions are as in (b). d Distributions of surround modulation index plotted separately for NCS-preferring units (with higher responses to NSC stimuli) and LDG-preferring units (with higher responses to LDG stimuli). LMEM test: Fstat. = 57.60, p = 1.73e-13 (**). e The IGRF1 is plotted against the complex-simple modulation index. Plotting conventions are as in (b). f The distribution of extracellular waveform TPL values for all recorded units. The dashed red line on the bimodal distribution shows the intersection of two distinct Gaussian distributions. Example spike waveforms are shown for one example unit from each distribution. Those with short TPL are putative interneurons, and those with long TPL are putative pyramidal neurons. g The percent of E units and I units with visually evoked responses to NCS and LDG stimuli. Two-sided Chi-squared test: χ2 = 6.28, p = 0.012 (*). h The mean IGR (left) and IGRF1 (right) magnitude of I units and E units (error bar = 95% Confidence Interval). LMEM test: F = 10.11, p = 1.56e-3 (left **); F = 10.68, p = 1.15e-3 (right **). i The mean IGR (left) and IGRF1 (right) magnitude of I and E non-overlapping units (error bar = 95% Confidence Interval). LMEM test: F = 2.51, p = 0.11 (left n.s); F = 1.04, p = 0.30 (right **). j, k NCS delay index plotted against RF-inducer distance for E units (n = 385) and I units (n = 221), respectively. The gray line in (h−k) is the least squared fit to the data. The Pearson correlation coefficient and the p value (two-sided t test) are shown. From (a−h), N = 6 mice. From (i−k) N = 13 mice. Source data are provided as a Source Data file.
