Table 1 TCB-enriched peptides identified in primary liver tissue
From: The physiological interactome of TCR-like antibody therapeutics in human tissues
Name | Sequence | A*02:01 Rank | Accession | Protein name | Intensity ratio (ESK1/MAGE) | -log10(p) | Esk1 JNFAT signal |
|---|---|---|---|---|---|---|---|
ILF2127-135 | KILPTLEAV | 0.051 | Q12905 | Interleukin enhancer-binding factor 2 | 64.0 | 4.59 | + |
RBM4B59-67 | KLHGVNINV | 0.03 | Q9BQ04 | RNA-binding protein 4B | 84.4 | 2.94 | ++ |
RL5117-125 | KIYEGQVEV | 0.004 | P46777 | 60 S ribosomal protein L5 | 4.6 | 2.67 | - |
SEPT2121-129 | YIDEQFERY | 1.77 | Q15019 | Septin-2 | 4.3 | 2.19 | - |
SET150-158 | KVLSKEFHL | 0.324 | Q01105 | Protein SET | 48.5 | 3.76 | - |
SF3B478-86 | KLYGKPIRV | 0.004 | Q15427 | Splicing factor 3B subunit 4 | 238.9 | 1.93 | + |
SHC1469-477 | RVPPPPQSV | 0.183 | P29353 | SHC-transforming protein 1 | 5.3 | 2.7 | ++ |
ARHGEF26863-871 | RLLGLETNV | 0.059 | Q96DR7 | Rho guanine nucleotide exchange factor 26 | 181.0 | 1.8 | ++ |
CRYL1130-138 | KLFAGLVHV | 0.004 | Q9Y2S2 | Lambda-crystallin homolog | 256.0 | 3.36 | ++ |
MSMO1164-172 | RIYKYIHKV | 0.03 | Q15800 | Methylsterol monooxygenase 1 | 13.0 | 2.94 | - |
CYP2C859-67 | KVYGPVFTV | 0.011 | P10632 | Cytochrome P450 2C8 | 22.6 | 3.6 | ++ |
USP9Y1674-1682 | RLWGEPVNL | 0.014 | O00507 | Prob. ubiquitin carboxyl-terminal hydrolase FAF-Y | 27.9 | 3.95 | ++ |
PLG92-100 | VLFEKKVYL | 0.008 | P00747 | Plasminogen | 4.9 | 2.67 | - |
MAF116-124 | ALISNSHQL | 0.038 | O75444 | Transcription factor Maf | 3.0 | 3 | - |
ALDOA216-224 | ALSDHHIYL | 0.011 | P04075 | Fructose-bisphosphate aldolase A | 3.5 | 2 | - |
HNRNPA115-23 | KLFIGGLSF | 1.625 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | 5.3 | 3.57 | - |
EIF3F348-357 | IALNEKLVNL | 0.613 | O00303 | Eukaryotic translation initiation factor 3 subunit F | 0.4 | 1.99 | - (MAGE-A4 TCB) |
