Fig. 2: Effect of reflex tears on tear glucose (TG) and tear volume (TV) level. | Nature Communications

Fig. 2: Effect of reflex tears on tear glucose (TG) and tear volume (TV) level.

From: In-depth correlation analysis between tear glucose and blood glucose using a wireless smart contact lens

Fig. 2

a Photograph showing the sequence for TG and TV monitoring after wearing smart contact lens (SCL). Scale bars, 1 cm. b Real-time measurement of TV when wearing SCL in normal rabbits (n = 4). c Real-time measurement of TG when wearing SCL in normal rabbits (n = 4). d, Comparison of TG level recovery time and TV recovery time after SCL wearing (n = 4). For (b–d) each data point represents the average of four normal rabbits, and the error bars indicate mean ± standard error of the mean. e Timeline of continuous measurement of blood glucose (BG), TG and TV along with conjunctival stimulation. f Photograph of external stimulation to the conjunctiva of rabbit using a von Frey filament. Scale bars, 1 cm. g Average of SMTube scores of four rabbits as a function of stimulating force (n = 4). Each data point represents the average of four normal rabbits, and the error bars indicate mean ± standard error of the mean. h Representative data of monitoring TG and BG levels (top) and relative changes in TV along with mechanical stimulation (bottom).

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