Fig. 4: The effect of absolute HDL-C change on cancer risk. | Nature Communications

Fig. 4: The effect of absolute HDL-C change on cancer risk.

From: A population-based cohort study of longitudinal change of high-density lipoprotein cholesterol impact on gastrointestinal cancer risk

Fig. 4

Adjusted hazard ratios (aHR) for gastric (a), colorectal (b), liver (c), pancreatic (d), gallbladder (e), and biliary cancers (f). ∆HDL-C = [(HDL-C at follow-up) − (HDL-C at baseline)]. X-axis is adjusted HR and y-axis is HDL-C change group. Adjusted HRs and CIs are derived from Cox proportional regression analysis. The dashed blue lines illustrate an HR of 1. The reference is a stable group. The HR is indicated with the central bar and the error bars show the 95% confidence interval (CI). Red bar is statistical significant HR with CI. ∆HDL < −10 (n = 561,153), ∆HDL = −10–−5 (n = 424,815), ∆HDL = −5–5 (n = 1,121,127), ∆HDL = 5–15 (n = 702993), ∆HDL = 15–25 (n = 234,723), ∆HDL ≥ 25 (n = 85,984). The exact hazard ratios and 95% confidence intervals are provided in Supplementary Table 8. HDL-C high-density lipoprotein cholesterol.

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